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Myelin/oligodendrocyte glycoprotein–deficient (MOG-deficient) mice reveal lack of immune tolerance to MOG in wild-type mice

We studied the immunological basis for the very potent encephalitogenicity of myelin/oligodendrocyte glycoprotein (MOG), a minor component of myelin in the CNS that is widely used to induce experimental autoimmune encephalomyelitis (EAE). For this purpose, we generated a mutant mouse lacking a funct...

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Detalhes bibliográficos
Main Authors: Delarasse, Cécile, Daubas, Philippe, Mars, Lennart T., Vizler, Csaba, Litzenburger, Tobias, Iglesias, Antonio, Bauer, Jan, Della Gaspera, Bruno, Schubart, Anna, Decker, Laurence, Dimitri, Dalia, Roussel, Guy, Dierich, Andrée, Amor, Sandra, Dautigny, André, Liblau, Roland, Pham-Dinh, Danielle
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC171383/
https://ncbi.nlm.nih.gov/pubmed/12925695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200315861
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