Direct comparison of a radioiodinated intact chimeric anti-CEA MAb with its F(ab')2 fragment in nude mice bearing different human colon cancer xenografts.

Tumour localisation and tumour to normal tissue ratios of a chimeric anti-carcinoembryonic antigen (CEA) monoclonal antibody (MAb), in intact form and as an F(ab')2 fragment labelled with 125I and 131I, were compared in groups of nude mice bearing four different colon cancer xenografts, T380, C...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Vogel, C. A., Bischof-Delaloye, A., Mach, J. P., Pèlegrin, A., Hardman, N., Delaloye, B., Buchegger, F.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1993
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968595/
https://ncbi.nlm.nih.gov/pubmed/8398694
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