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Pharmacology and antitumour effects of intraportal pirarubicin on experimental liver metastases.

Early liver metastases have a predominant portal blood supply. Intraportal (i.port.) vein administration of cytotoxics could theoretically achieve enhanced drug concentrations in tumour cells and be effective as adjuvant therapy after resection of colorectal carcinoma. Pirarubicin (which has a highe...

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Hlavní autoři: Ramirez, L. H., Munck, J. N., Bognel, C., Zhao, Z., Ardouin, P., Poupon, M. F., Gouyette, A., Rougier, P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1993
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968574/
https://ncbi.nlm.nih.gov/pubmed/8347482
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