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Pharmacology and antitumour effects of intraportal pirarubicin on experimental liver metastases.

Early liver metastases have a predominant portal blood supply. Intraportal (i.port.) vein administration of cytotoxics could theoretically achieve enhanced drug concentrations in tumour cells and be effective as adjuvant therapy after resection of colorectal carcinoma. Pirarubicin (which has a highe...

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Bibliografiske detaljer
Main Authors: Ramirez, L. H., Munck, J. N., Bognel, C., Zhao, Z., Ardouin, P., Poupon, M. F., Gouyette, A., Rougier, P.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1993
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968574/
https://ncbi.nlm.nih.gov/pubmed/8347482
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