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High prevalence of mutations at codon 249 of the p53 gene in hepatocellular carcinomas from Senegal.

In hepatocellular carcinoma, mutation within the p53 gene occurs mainly at codon 249 and its frequency has been associated with exposure to aflatoxin. As Senegal is a country where liver cancer incidence is one of the highest in the world and where people are highly exposed to aflatoxin, we screened...

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Autori principali: Coursaget, P., Depril, N., Chabaud, M., Nandi, R., Mayelo, V., LeCann, P., Yvonnet, B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1993
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968506/
https://ncbi.nlm.nih.gov/pubmed/8390289
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