The TP53 tumour suppressor gene in colorectal carcinomas. II. Relation to DNA ploidy pattern and clinicopathological variables.

Heterozygous loss of the TP53 gene on chromosome arm 17p in colorectal carcinomas was strongly associated with DNA aneuploidy (P < 0.0001). This association was seen only in tumours with loss on both 17p and 17q (P < 0.001), but not for loss on 17p only. DNA near diploid (ND) carcinomas and DN...

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Bibliografische gegevens
Hoofdauteurs: Meling, G. I., Lothe, R. A., Børresen, A. L., Graue, C., Hauge, S., Clausen, O. P., Rognum, T. O.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 1993
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968222/
https://ncbi.nlm.nih.gov/pubmed/8427784
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