Synchronization of Interphase Events Depends neither on Mitosis nor on cdk1

Human HT2-19 cells with a conditional cdk1 mutation stop dividing upon cdk1 inactivation and undergo multiple rounds of endoreplication. We show herein that major cell cycle events remain synchronized in these endoreplicating cells. DNA replication alternates with gap phases and cell cycle-specific...

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Main Authors: Laronne, Ayelet, Rotkopf, Shay, Hellman, Asaf, Gruenbaum, Yosef, Porter, Andrew C.G., Brandeis, Michael
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2003
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC196563/
https://ncbi.nlm.nih.gov/pubmed/12972560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-12-0850
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