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Identification of an mRNA-Decapping Regulator Implicated in X-Linked Mental Retardation

Two major decapping enzymes are involved in the decay of eukaryotic mRNA, Dcp2 and DcpS. Despite the detection of robust DcpS decapping activity in cell extract, minimal to no decapping is detected from human Dcp2 (hDcp2) in extract. We now demonstrate that one reason for the lack of detectable hDcp...

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書誌詳細
主要な著者: Jiao, Xinfu, Wang, Zuoren, Kiledjian, Megerditch
フォーマット: Artigo
言語:Inglês
出版事項: 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965588/
https://ncbi.nlm.nih.gov/pubmed/17157254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.10.013
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