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Identification of an mRNA-Decapping Regulator Implicated in X-Linked Mental Retardation

Two major decapping enzymes are involved in the decay of eukaryotic mRNA, Dcp2 and DcpS. Despite the detection of robust DcpS decapping activity in cell extract, minimal to no decapping is detected from human Dcp2 (hDcp2) in extract. We now demonstrate that one reason for the lack of detectable hDcp...

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Hlavní autoři: Jiao, Xinfu, Wang, Zuoren, Kiledjian, Megerditch
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965588/
https://ncbi.nlm.nih.gov/pubmed/17157254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.10.013
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