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Mutational analysis of a viral RNA element that counteracts rapid RNA decay by interaction with the polyadenylate tail

We previously demonstrated that the Kaposi's sarcoma-associated herpesvirus polyadenylated nuclear RNA contains a 79-nt cis-acting element, the ENE, which allows intronless polyadenylated transcripts to accumulate to high nuclear levels by protecting them from rapid degradation. We proposed a m...

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Detalhes bibliográficos
Main Authors: Conrad, Nicholas K., Shu, Mei-Di, Uyhazi, Katherine E., Steitz, Joan A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965527/
https://ncbi.nlm.nih.gov/pubmed/17563387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704187104
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