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Structural basis for streptogramin B resistance in Staphylococcus aureus by virginiamycin B lyase

The streptogramin combination therapy of quinupristin–dalfopristin (Synercid) is used to treat infections caused by bacterial pathogens, such as methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium. However, the effectiveness of this therapy is being compromised...

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Detalhes bibliográficos
Main Authors: Korczynska, Magdalena, Mukhtar, Tariq A., Wright, Gerard D., Berghuis, Albert M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965523/
https://ncbi.nlm.nih.gov/pubmed/17563376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701809104
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