Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation

Acyl-CoA thioesterases (Acots) catalyze the hydrolysis of fatty acyl-CoA to free fatty acid and CoA and thereby regulate lipid metabolism and cellular signaling. We present a comprehensive structural and functional characterization of mouse acyl-CoA thioesterase 7 (Acot7). Whereas prokaryotic homolo...

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Detalles Bibliográficos
Autores principales: Forwood, Jade K., Thakur, Anil S., Guncar, Gregor, Marfori, Mary, Mouradov, Dmitri, Meng, Weining, Robinson, Jodie, Huber, Thomas, Kellie, Stuart, Martin, Jennifer L., Hume, David A., Kobe, Bostjan
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2007
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965522/
https://ncbi.nlm.nih.gov/pubmed/17563367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700974104
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