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The Akt C-Terminal Modulator Protein Is an Acyl-CoA Thioesterase of the Hotdog-Fold Family

Herein, we report on an in vitro kinetic activity analysis that demonstrates that the protein known as the Akt C-terminal modulator protein is a broad-range, high-activity acyl-CoA thioesterase. In vitro tests of possible activity regulation by product inhibition or by Akt1 binding gave negative res...

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Detalhes bibliográficos
Main Authors: Zhao, Hong, Martin, Brian M., Bisoffi, Marco, Dunaway-Mariano, Debra
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803014/
https://ncbi.nlm.nih.gov/pubmed/19453107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900710w
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