Lipid Raft Targeting of the TC10 Amino Terminal Domain Is Responsible for Disruption of Adipocyte Cortical Actin

Overexpression of the Rho family member TC10α, disrupts adipocyte cortical actin structure and inhibits insulin-stimulated GLUT4 translocation when targeted to lipid raft microdomains. This appears to be independent of effecter domain function because overexpression of the wild-type (TC10/WT), const...

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Pubblicato in:	Mol Biol Cell
Autori principali:	Chunqiu Hou, June, Pessin, Jeffrey E.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Cell Biology 2003
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196551/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12972548/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-01-0012
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