Lipid Raft Targeting of the TC10 Amino Terminal Domain Is Responsible for Disruption of Adipocyte Cortical Actin

Overexpression of the Rho family member TC10α, disrupts adipocyte cortical actin structure and inhibits insulin-stimulated GLUT4 translocation when targeted to lipid raft microdomains. This appears to be independent of effecter domain function because overexpression of the wild-type (TC10/WT), const...

Full description

Bibliographic Details

Published in:	Mol Biol Cell
Main Authors:	Chunqiu Hou, June, Pessin, Jeffrey E.
Format:	Artigo
Language:	Inglês
Published:	American Society for Cell Biology 2003
Subjects:	Articles
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196551/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12972548/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-01-0012
Tags:	Add Tag No Tags, Be the first to tag this record!