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Serial Perturbation of MinK in I(Ks) Implies an α-Helical Transmembrane Span Traversing the Channel Corpus
I(Ks) channels contain four pore-forming KCNQ1 subunits and two accessory MinK subunits. MinK influences surface expression, voltage-dependence of gating, conduction, and pharmacology to yield the attributes characteristic of native channels in heart. The structure and location of the MinK transmemb...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1965433/ https://ncbi.nlm.nih.gov/pubmed/17545244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.109702 |
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