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Long-term colonic hypersensitivity in adult rats induced by neonatal unpredictable vs predictable shock

Our goal was to examine the relationship between early life trauma and the development of visceral hypersensitivity in later life in irritable bowel syndrome (IBS). Rat pups underwent neonatal conditioning: (i) paired odour-shock, where odour is a predictable shock signal, (ii) unpaired odour-shock,...

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Main Authors: TYLER, K., MORICEAU, S., SULLIVAN, R. M., MEERVELD, B. GREENWOOD-VAN
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1964755/
https://ncbi.nlm.nih.gov/pubmed/17727395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2982.2007.00955.x
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