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Importance of neural mechanisms in colonic mucosal and muscular dysfunction in adult rats following neonatal colonic irritation
Previous studies have shown that early life trauma induced by maternal separation or colonic irritation leads to hypersensitivity to colorectal distension in adulthood. We tested the hypothesis that repetitive colorectal distension in neonates leads to abnormalities in colonic permeability and smoot...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3327121/ https://ncbi.nlm.nih.gov/pubmed/19766182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijdevneu.2009.09.001 |
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