SIRT1 Activation Confers Neuroprotection in Experimental Optic Neuritis

PURPOSE: Axonal damage and loss of neurons correlate with permanent vision loss and neurologic disability in patients with optic neuritis and multiple sclerosis (MS). Current therapies involve immunomodulation, with limited effects on neuronal damage. The authors examined potential neuroprotective e...

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Hlavní autoři: Shindler, Kenneth S., Ventura, Elvira, Rex, Tonia S., Elliott, Peter, Rostami, Abdolmohamad
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1964753/
https://ncbi.nlm.nih.gov/pubmed/17652729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.07-0131
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