Pcl-PRC2 is needed to generate high levels of H3-K27 trimethylation at Polycomb target genes

PRC2 is thought to be the histone methyltransferase (HMTase) responsible for H3-K27 trimethylation at Polycomb target genes. Here we report the biochemical purification and characterization of a distinct form of Drosophila PRC2 that contains the Polycomb group protein polycomblike (Pcl). Like PRC2,...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Nekrasov, Maxim, Klymenko, Tetyana, Fraterman, Sven, Papp, Bernadett, Oktaba, Katarzyna, Köcher, Thomas, Cohen, Adrian, Stunnenberg, Hendrik G, Wilm, Matthias, Müller, Jürg
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2007
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1964751/
https://ncbi.nlm.nih.gov/pubmed/17762866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601837
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky