Osteopontin mediates obesity-induced adipose tissue macrophage infiltration and insulin resistance in mice

Obesity is associated with a state of chronic, low-grade inflammation characterized by abnormal cytokine production and macrophage infiltration into adipose tissue, which may contribute to the development of insulin resistance. During immune responses, tissue infiltration by macrophages is dependent...

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Hlavní autoři: Nomiyama, Takashi, Perez-Tilve, Diego, Ogawa, Daisuke, Gizard, Florence, Zhao, Yue, Heywood, Elizabeth B., Jones, Karrie L., Kawamori, Ryuzo, Cassis, Lisa A., Tschöp, Matthias H., Bruemmer, Dennis
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2007
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1964510/
https://ncbi.nlm.nih.gov/pubmed/17823662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31986
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