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The primordial metabolism: an ancestral interconnection between leucine, arginine, and lysine biosynthesis

BACKGROUND: It is generally assumed that primordial cells had small genomes with simple genes coding for enzymes able to react with a wide range of chemically related substrates, interconnecting different metabolic routes. New genes coding for enzymes with a narrowed substrate specificity arose by p...

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Bibliographic Details
Main Authors: Fondi, Marco, Brilli, Matteo, Emiliani, Giovanni, Paffetti, Donatella, Fani, Renato
Format: Artigo
Language:Inglês
Published: BioMed Central|1 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1963480/
https://ncbi.nlm.nih.gov/pubmed/17767731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-7-S2-S3
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