Sex Differences in the Effect of Finasteride on Acute Ethanol Withdrawal Severity in C57BL/6J and DBA/2J Mice

The neurosteroid allopregnanolone (ALLO) is a potent positive modulator of γ-aminobutyric acid(A) (GABA(A)) receptors that can modulate ethanol (EtOH) withdrawal. The 5α-reductase inhibitor finasteride can block the formation of ALLO and other GABAergic neurosteroids and also reduce certain effects...

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Hlavní autoři: Gorin-Meyer, Rebecca E., Wiren, Kristine M., Tanchuck, Michelle A., Long, Season L., Yoneyama, Naomi, Finn, Deborah A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1963463/
https://ncbi.nlm.nih.gov/pubmed/17428611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2007.02.051
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