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Sex Differences in the Effect of Finasteride on Acute Ethanol Withdrawal Severity in C57BL/6J and DBA/2J Mice
The neurosteroid allopregnanolone (ALLO) is a potent positive modulator of γ-aminobutyric acid(A) (GABA(A)) receptors that can modulate ethanol (EtOH) withdrawal. The 5α-reductase inhibitor finasteride can block the formation of ALLO and other GABAergic neurosteroids and also reduce certain effects...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1963463/ https://ncbi.nlm.nih.gov/pubmed/17428611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2007.02.051 |
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