Identification of a single amino acid substitution in the diphtheria toxin A chain of CRM 228 responsible for the loss of enzymatic activity.

CRM 228 (T. Uchida, A. M. Pappenheimer, and R. Greany, J. Biol. Chem. 248:3838-3844, 1973), a mutant form of diphtheria toxin which completely lacks ADP-ribosyltransferase activity, contains five amino acid substitutions. The two amino acid changes that fall within the A chain of the toxin (G79D and...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Johnson, V G, Nicholls, P J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196302/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8045910/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.15.4766-4769.1994
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