BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system

Mammalian CLOCK and BMAL1 are two members of bHLH-PAS-containing family of transcription factors that represent the positive elements of circadian autoregulatory feedback loop. In the form of a heterodimer, they drive transcription from E-box enhancer elements in the promoters of responsive genes. W...

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Pubblicato in:	Genes Dev
Autori principali:	Kondratov, Roman V., Chernov, Mikhail V., Kondratova, Anna A., Gorbacheva, Victoria Y., Gudkov, Andrei V., Antoch, Marina P.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 2003
Soggetti:	Research Papers
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196247/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12897057/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1099503
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