Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: a mammalian cell culture model of gene variegation

Heterochromatin protein 1 (HP1) is a key component of constitutive heterochromatin in Drosophila and is required for stable epigenetic gene silencing classically observed as position effect variegation. Less is known of the family of mammalian HP1 proteins, which may be euchromatic, targeted to expr...

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Hlavní autoři: Ayyanathan, Kasirajan, Lechner, Mark S., Bell, Peter, Maul, Gerd G., Schultz, David C., Yamada, Yoshihiko, Tanaka, Kazuhiro, Torigoe, Kiyoyuki, Rauscher, Frank J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2003
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC196232/
https://ncbi.nlm.nih.gov/pubmed/12869583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1102803
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