SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins

Posttranslational modification of histones has emerged as a key regulatory signal in eukaryotic gene expression. Recent genetic and biochemical studies link H3-lysine 9 (H3-K9) methylation to HP1-mediated heterochromatin formation and gene silencing. However, the mechanisms that target and coordinat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Schultz, David C., Ayyanathan, Kasirajan, Negorev, Dmitri, Maul, Gerd G., Rauscher, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152359/
https://ncbi.nlm.nih.gov/pubmed/11959841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.973302
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados