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SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins

Posttranslational modification of histones has emerged as a key regulatory signal in eukaryotic gene expression. Recent genetic and biochemical studies link H3-lysine 9 (H3-K9) methylation to HP1-mediated heterochromatin formation and gene silencing. However, the mechanisms that target and coordinat...

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書誌詳細
主要な著者: Schultz, David C., Ayyanathan, Kasirajan, Negorev, Dmitri, Maul, Gerd G., Rauscher, Frank J.
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC152359/
https://ncbi.nlm.nih.gov/pubmed/11959841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.973302
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