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Reduction in receptors for bombesin and epidermal growth factor in xenografts of human small-cell lung cancer after treatment with bombesin antagonist RC-3095

Antagonists of bombesin/gastrin-releasing peptide (BN/GRP) have been developed to inhibit the stimulatory effects of BN/GRP on the mitogenesis of tumor cells such as human small-cell lung carcinoma (SCLC). The mode of action of these antagonists is not completely understood. In this study, we evalua...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Halmos, Gabor, Schally, Andrew V.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1997
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19621/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9023364/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.3.956
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