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5-Methylcytosine is not a mutation hot spot in nondividing Escherichia coli

Spontaneous deamination of 5-methylcytosine (5meC) causes hot spots of C·G → T·A mutations in Escherichia coli and in human cells. In E. coli, the resulting T·G mispairs can be corrected to C·G by very short patch (VSP) repair, which requires the product of gene vsr. Mutation hot spots in genes of r...

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Bibliografske podrobnosti
Main Authors: Lieb, Margaret, Rehmat, Shehnaz
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences of the USA 1997
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC19618/
https://ncbi.nlm.nih.gov/pubmed/9023361
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