5-Methylcytosine is not a mutation hot spot in nondividing Escherichia coli
Spontaneous deamination of 5-methylcytosine (5meC) causes hot spots of C·G → T·A mutations in Escherichia coli and in human cells. In E. coli, the resulting T·G mispairs can be corrected to C·G by very short patch (VSP) repair, which requires the product of gene vsr. Mutation hot spots in genes of r...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1997
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19618/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9023361/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.3.940 |
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