Regulated CPEB phosphorylation during meiotic progression suggests a mechanism for temporal control of maternal mRNA translation

CPEB is an mRNA-binding protein that stimulates polyadenylation-induced translation of maternal mRNA once it is phosphorylated on Ser 174 or Thr 171 (species-dependent). Disruption of the CPEB gene in mice causes an arrest of oogenesis at embryonic day 16.5 (E16.5), when most oocytes are in pachyten...

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Vydáno v:	Genes Dev
Hlavní autoři:	Tay, Joyce, Hodgman, Rebecca, Sarkissian, Madathia, Richter, Joel D.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Cold Spring Harbor Laboratory Press 2003
Témata:	Research Communications
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196075/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12815066/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1071403
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