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RNA polymerase mutations that impair conversion to a termination-resistant complex by Q antiterminator proteins
Bacteriophage λ Q-protein stably binds and modifies RNA polymerase (RNAP) to a termination-resistant form. We describe amino acid substitutions in RNAP that disrupt Q-mediated antitermination in vivo and in vitro. The positions of these substitutions in the modeled RNAP/DNA/RNA ternary elongation co...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC196057/ https://ncbi.nlm.nih.gov/pubmed/12756229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1082103 |
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