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Activation of the cell death program by inhibition of proteasome function

Activation of proteolytic enzymes, including cysteine proteases of the ced-3/ICE family, is a characteristic feature of the apoptotic program. In contrast, the role of the proteasome as the major nonlysosomal machinery to degrade or process proteins by ATP/ubiquitin-dependent proteolysis in this pro...

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Autor principal: Drexler, Hannes C. A.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC19603/
https://ncbi.nlm.nih.gov/pubmed/9023346
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