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Translational control by TOR and TAP42 through dephosphorylation of eIF2α kinase GCN2
Yeast protein kinase GCN2 stimulates the translation of transcriptional activator GCN4 by phosphorylating eIF2α in response to amino acid starvation. Kinase activation requires binding of uncharged tRNA to a histidyl tRNA synthetase-related domain in GCN2. Phosphorylation of serine 577 (Ser 577) in...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2003
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC196024/ https://ncbi.nlm.nih.gov/pubmed/12654728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1069003 |
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