Translational control by TOR and TAP42 through dephosphorylation of eIF2α kinase GCN2

Yeast protein kinase GCN2 stimulates the translation of transcriptional activator GCN4 by phosphorylating eIF2α in response to amino acid starvation. Kinase activation requires binding of uncharged tRNA to a histidyl tRNA synthetase-related domain in GCN2. Phosphorylation of serine 577 (Ser 577) in...

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Bibliografski detalji

Izdano u:	Genes Dev
Glavni autori:	Cherkasova, Vera A., Hinnebusch, Alan G.
Format:	Artigo
Jezik:	Inglês
Izdano:	Cold Spring Harbor Laboratory Press 2003
Teme:	Research Paper
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196024/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12654728/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1069003
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