Human and mouse TPIT gene mutations cause early onset pituitary ACTH deficiency

Tpit is a highly cell-restricted transcription factor that is required for expression of the pro-opiomelanocortin (POMC) gene and for terminal differentiation of the pituitary corticotroph lineage. Its exclusive expression in pituitary POMC-expressing cells has suggested that its mutation may cause...

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Detalhes bibliográficos
Main Authors: Pulichino, Anne-Marie, Vallette-Kasic, Sophie, Couture, Catherine, Gauthier, Yves, Brue, Thierry, David, Michel, Malpuech, Georges, Deal, Cheri, Van Vliet, Guy, De Vroede, Monique, Riepe, Felix G., Partsch, Carl-Joachim, Sippell, Wolfgang G., Berberoglu, Merih, Atasay, Begüm, Drouin, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC196015/
https://ncbi.nlm.nih.gov/pubmed/12651888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1065603
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