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siRNAs can function as miRNAs

With the discovery of RNA interference (RNAi) and related phenomena, new regulatory roles attributed to RNA continue to emerge. Here we show, in mammalian tissue culture, that a short interfering RNA (siRNA) can repress expression of a target mRNA with partially complementary binding sites in its 3′...

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Podrobná bibliografie
Hlavní autoři: Doench, John G., Petersen, Christian P., Sharp, Phillip A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC195999/
https://ncbi.nlm.nih.gov/pubmed/12600936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1064703
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