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EGF-CFC proteins are essential coreceptors for the TGF-β signals Vg1 and GDF1

The TGF-β signals Nodal, Activin, GDF1, and Vg1 have been implicated in mesoderm induction and left-right patterning. Nodal and Activin both activate Activin receptors, but only Nodal requires EGF-CFC coreceptors for signaling. We report that Vg1 and GDF1 signaling in zebrafish also depends on EGF-C...

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Detalhes bibliográficos
Main Authors: Cheng, Simon K., Olale, Felix, Bennett, James T., Brivanlou, Ali H., Schier, Alexander F.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC195969/
https://ncbi.nlm.nih.gov/pubmed/12514096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1041203
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