Telomere-based crisis: functional differences between telomerase activation and ALT in tumor progression

Telomerase activation is a common feature of most advanced human cancers and is postulated to restore genomic stability to a level permissive for cell viability and tumor progression. Here, we used genetically defined transformed mouse embryonic fibroblast (MEF) cultures derived from late generation...

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Detalles Bibliográficos

Publicado en:	Genes Dev
Autores principales:	Chang, Sandy, Khoo, Christine M., Naylor, Maria L., Maser, Richard S., DePinho, Ronald A.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Cold Spring Harbor Laboratory Press 2003
Materias:	Research Paper
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC195968/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12514102/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1029903
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