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Dynamics of Firefly Luciferase Inhibition by General Anesthetics: Gaussian and Anisotropic Network Analyses

The new crystal structures of the product-bound firefly luciferase combined with the previously determined substrate-free structures allow for a detailed analysis of the dynamics basis for the luciferase enzymatic activities. Using the Gaussian network model and the anisotropic network model, we sho...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Szarecka, Agnieszka, Xu, Yan, Tang, Pei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biophysical Society 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1959537/
https://ncbi.nlm.nih.gov/pubmed/17513367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.102780
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