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The Permeability Enhancing Mechanism of DMSO in Ceramide Bilayers Simulated by Molecular Dynamics

The lipids of the topmost layer of the skin, the stratum corneum, represent the primary barrier to molecules penetrating the skin. One approach to overcoming this barrier for the purpose of delivery of active molecules into or via the skin is to employ chemical permeability enhancers, such as dimeth...

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Detalhes bibliográficos
Main Authors: Notman, Rebecca, den Otter, Wouter K., Noro, Massimo G., Briels, W. J., Anwar, Jamshed
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1959535/
https://ncbi.nlm.nih.gov/pubmed/17513383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.104703
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