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Computational Prediction of Atomic Structures of Helical Membrane Proteins Aided by EM Maps

Integral membrane proteins pose a major challenge for protein-structure prediction because only ≈100 high-resolution structures are available currently, thereby impeding the development of rules or empirical potentials to predict the packing of transmembrane α-helices. However, when an intermediate-...

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Autors principals: Kovacs, Julio A., Yeager, Mark, Abagyan, Ruben
Format: Artigo
Idioma:Inglês
Publicat: Biophysical Society 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1959528/
https://ncbi.nlm.nih.gov/pubmed/17496035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.102137
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