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Selective Impairment of Nuclear Factor-κB-Dependent Gene Transcription in Adult Cardiomyocytes : Relevance for the Regulation of the Inflammatory Response in the Heart
The ability of neonatal and adult cardiomyocytes to activate the nuclear factor (NF)-κB pathway in response to lipopolysaccharide and interleukin-1β challenge has been investigated and compared with that of peritoneal macrophages. The activation of the IκB kinase and the phosphorylation and degradat...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Investigative Pathology
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1959507/ https://ncbi.nlm.nih.gov/pubmed/17675583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.061076 |
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