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Selective Impairment of Nuclear Factor-κB-Dependent Gene Transcription in Adult Cardiomyocytes : Relevance for the Regulation of the Inflammatory Response in the Heart

The ability of neonatal and adult cardiomyocytes to activate the nuclear factor (NF)-κB pathway in response to lipopolysaccharide and interleukin-1β challenge has been investigated and compared with that of peritoneal macrophages. The activation of the IκB kinase and the phosphorylation and degradat...

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Main Authors: Cuenca, Jimena, Goren, Nora, Prieto, Patricia, Martín-Sanz, Paloma, Boscá, Lisardo
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1959507/
https://ncbi.nlm.nih.gov/pubmed/17675583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.061076
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