Aldosterone Induces Elastin Production in Cardiac Fibroblasts through Activation of Insulin-Like Growth Factor-I Receptors in a Mineralocorticoid Receptor-Independent Manner

Aldosterone is known to regulate electrolyte homeostasis, but it may also contribute to other processes, including the maladaptive remodeling of postinfarct hearts. Because aldosterone has been implicated in the stimulation of collagen production in the heart, we investigated whether it would also a...

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Detalhes bibliográficos
Main Authors: Bunda, Severa, Liu, Peter, Wang, Yanting, Liu, Kela, Hinek, Aleksander
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1959490/
https://ncbi.nlm.nih.gov/pubmed/17724138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070101
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