Targeted Skin Overexpression of the Mineralocorticoid Receptor in Mice Causes Epidermal Atrophy, Premature Skin Barrier Formation, Eye Abnormalities, and Alopecia

The mineralocorticoid receptor (MR) is a transcription factor of the nuclear receptor family, activation of which by aldosterone enhances salt reabsorption in the kidney. The MR is also expressed in nonclassical aldosterone target cells (brain, heart, and skin), in which its functions are incomplete...

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Detalhes bibliográficos
Main Authors: Sainte Marie, Yannis, Toulon, Antoine, Paus, Ralf, Maubec, Eve, Cherfa, Aicha, Grossin, Maggy, Descamps, Vincent, Clemessy, Maud, Gasc, Jean-Marie, Peuchmaur, Michel, Glick, Adam, Farman, Nicolette, Jaisser, Frederic
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1959477/
https://ncbi.nlm.nih.gov/pubmed/17675581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060991
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