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A chicken model of pharmacologically-induced Hirschsprung disease reveals an unexpected role of glucocorticoids in enteric aganglionosis

The enteric nervous system originates from neural crest cells that migrate in chains as they colonize the embryonic gut, eventually forming the myenteric and submucosal plexus. Failure of the neural crest cells to colonize the gut leads to aganglionosis in the terminal gut, a pathological condition...

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Detalles Bibliográficos
Publicado en:Biol Open
Main Authors: Gasc, Jean-Marie, Clemessy, Maud, Corvol, Pierre, Kempf, Hervé
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434818/
https://ncbi.nlm.nih.gov/pubmed/25836673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.201410454
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