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Yeast aconitase binds and provides metabolically coupled protection to mitochondrial DNA
Aconitase (Aco1p) is a multifunctional protein: It is an enzyme of the tricarboxylic acid cycle. In animal cells, Aco1p also is a cytosolic protein binding to mRNAs to regulate iron metabolism. In yeast, Aco1p was identified as a component of mtDNA nucleoids. Here we show that yeast Aco1p protects m...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1959452/ https://ncbi.nlm.nih.gov/pubmed/17698960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703078104 |
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