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Yeast aconitase binds and provides metabolically coupled protection to mitochondrial DNA

Aconitase (Aco1p) is a multifunctional protein: It is an enzyme of the tricarboxylic acid cycle. In animal cells, Aco1p also is a cytosolic protein binding to mRNAs to regulate iron metabolism. In yeast, Aco1p was identified as a component of mtDNA nucleoids. Here we show that yeast Aco1p protects m...

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Bibliografische gegevens
Hoofdauteurs: Chen, Xin Jie, Wang, Xiaowen, Butow, Ronald A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1959452/
https://ncbi.nlm.nih.gov/pubmed/17698960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703078104
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