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The numbers of individual mitochondrial DNA molecules and mitochondrial DNA nucleoids in yeast are co-regulated by the general amino acid control pathway
Mitochondrial DNA (mtDNA) is inherited as a protein–DNA complex (the nucleoid). We show that activation of the general amino acid response pathway in ρ(+) and ρ(–) petite cells results in an increased number of nucleoids without an increase in mtDNA copy number. In ρ(–) cells, activation of the gene...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305615/ https://ncbi.nlm.nih.gov/pubmed/10675346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.4.767 |
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