Mutation in Mouse Hei10, an E3 Ubiquitin Ligase, Disrupts Meiotic Crossing Over

Crossing over during meiotic prophase I is required for sexual reproduction in mice and contributes to genome-wide genetic diversity. Here we report on the characterization of an N-ethyl-N-nitrosourea-induced, recessive allele called mei4, which causes sterility in both sexes owing to meiotic defect...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ward, Jeremy O, Reinholdt, Laura G, Motley, William W, Niswander, Lisa M, Deacon, Dekker C, Griffin, Laurie B, Langlais, Kristofor K, Backus, Vickie L, Schimenti, Kerry J, O'Brien, Marilyn J, Eppig, John J, Schimenti, John C
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2007
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1959360/
https://ncbi.nlm.nih.gov/pubmed/17784788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030139
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