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Spata22, a Novel Vertebrate-Specific Gene, Is Required for Meiotic Progress in Mouse Germ Cells

The N-ethyl-N-nitrosourea-induced repro42 mutation, identified by a forward genetics strategy, causes both male and female infertility, with no other apparent phenotypes. Positional cloning led to the discovery of a nonsense mutation in Spata22, a hitherto uncharacterized gene conserved among bony v...

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Detalhes bibliográficos
Main Authors: La Salle, Sophie, Palmer, Kristina, O'Brien, Marilyn, Schimenti, John C., Eppig, John, Handel, Mary Ann
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290669/
https://ncbi.nlm.nih.gov/pubmed/22011390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.111.095752
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