Inhibition of tumorigenesis by a cytosine–DNA, methyltransferase, antisense oligodeoxynucleotide

This paper tests the hypothesis that cytosine DNA methyltransferase (DNA MeTase) is a candidate target for anticancer therapy. Several observations have suggested recently that hyperactivation of DNA MeTase plays a critical role in initiation and progression of cancer and that its up-regulation is a...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Ramchandani, Shyam, MacLeod, A. Robert, Pinard, Marc, von Hofe, Eric, Szyf, Moshe
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1997
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19574/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9012845/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.2.684
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